PRESS RELEASES

Oxis International, Inc. Announces Appointment of Michael S. Sitrick to Business Advisory Board
 

TAMPA, Fla., Oct. 5, 2015 -- Oxis International, Inc. [OTC: OXIS] [Euronext Paris: OXI.PA] announced today that Michael S. Sitrick has joined its Business Advisory Board. Oxis is in the process of building a world class Business Advisory Board to assist management in strategy, development and execution. The Business Advisory Board members will become members of the Oxis Board of Directors upon a successful up-listing to the NASDAQ exchange.

Mr. Sitrick, who is a former board member of APP Pharmaceuticals Company and Abraxis BioScience, is the founder, Chairman and Chief Executive Officer of Sitrick And Company, an internationally recognized strategic communications firm. Since founding that firm, he has provided advice and counsel to more than 1,000 companies, including some of the nation's largest corporations, and some of its highest profile individuals -- both on routine and extremely sensitive matters. In the bio-tech and pharmaceutical area these clients have included such companies as Amgen, Glaxo Smith-Kline and Biovail.

Mr. Sitrick currently serves on the Board of Directors of Jakks Pacific. Mr. Sitrick holds a B.S. in Business Administration with a major in Journalism from the University of Maryland, College Park.

"Mike Sitrick is not only one of the nation's leading strategic communications experts, but also has a wealth of experience and knowledge in management, corporate governance and value creation. His accomplishments and client list speak for themselves. We are excited that he has agreed to join our Business Advisory Board and look forward to his contributions to the company," said Anthony Cataldo, Chairman and CEO of Oxis Biotech.

"Oxis is at the forefront of developing new cancer treatments. The company is an example of doing well by doing good. I am pleased to be able to contribute to its growth and success," said Mr. Sitrick.

ABOUT OXIS BIOTECH, INC. - Oxis Biotech develops innovative drugs focused on the treatment of cancer and other unmet medical needs. OXIS' lead drug candidate, DT2219ARL is a novel bispecific scFv recombinant fusion protein-drug conjugate composed of the variable regions of the heavy and light chains of anti-CD19 and anti-CD22 antibodies and a modified form of diphtheria toxin as its cytotoxic drug payload. DT2219ARL simultaneously targets cancer cells expressing the CD19 receptor or CD22 receptor or both receptors. When DT2219ARL binds to cancer cells, the cancer cells internalize DT2219ARL and are killed due to the action of drug's cytotoxic payload. DT2219ARL has demonstrated success in early human clinical trials in patients with relapsed/refractory B-cell lymphoma or leukemia. OXS-4235 is a small molecule therapeutic candidate targeting the treatment of multiple myeloma and associated osteolytic lesions. In in vitro and in vivo models of multiple myeloma and osteoporosis, OXS-4235 demonstrated the ability to kill multiple myeloma cells, and decrease osteolytic lesions in bone. OXIS' lead drug candidate, OXS-2175, is a small molecule therapeutic candidate targeting the treatment of triple-negative breast cancer (TNBC). In in vitro and in vivo models of TNBC, OXS-2175 demonstrated the ability to inhibit metastasis. For more information about Oxis Biotech, please visit http://www.oxis.com.

Forward-Looking Statements - Except for historical information contained herein, the statements in this release are forward-looking and made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are inherently unreliable and actual results may differ materially. Examples of forward-looking statements in this news release include statements regarding the payment of dividends, marketing and distribution plans, development activities and anticipated operating results. Factors which could cause actual results to differ materially from these forward-looking statements include such factors as the Company's ability to accomplish its business initiatives, significant fluctuations in marketing expenses and ability to achieve and expand significant levels of revenues, or recognize net income, from the sale of its products and services, as well as the introduction of competing products, or management's ability to attract and maintain qualified personnel necessary for the development and commercialization of its planned products, and other information that may be detailed from time to time in the Company's filings with the United States Securities and Exchange Commission. The Company undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

 

Oxis Biotech Inc. Announces Appointment of Randolph C Read to Business Advisory Board
 

TAMPA, Fla., Sept. 24, 2015 -- Oxis Biotech, Inc. (OXIS), a wholly owned subsidiary of Oxis International, Inc. [OTC: OXIS] and [Euronext Paris: OXI.PA] announced today, Randolph C Read has joined its Business Advisory Board. Oxis is in the process of building a world class Advisory Board to assist management in strategy, development and execution. The Business Advisory Board members will become members of the Oxis Board of Directors upon a successful up-listing to the NASDAQ exchange.

Randolph C. Read has been President and Chief Executive Officer of Nevada Strategic Credit Investments, LLC since 2009. Mr. Read has previously served as President of a variety of other companies, including International Capital Markets Group, Inc. Mr. Read serves on the Boards of Directors of New York REIT, Inc. (as Chairman) a NYSE listed company (NYRT), Healthcare Trust, Inc. (as Chairman), Business Development Corporation of America, and the advisory board of the Flying Food Group, LLC and has previously served on a number of public and private company boards. He has an M.B.A. in Finance from the Wharton Graduate School of the University of Pennsylvania.

"Randy is a vital part of the Oxis plan to be a major biotech company. We are excited to have him on our Advisory Board. Oxis Biotech, Inc. will continue to bring in major biotech assets and surround ourselves with key executives.

"I am very pleased to be joining the Advisory Board of Oxis Biotech, which is attempting to achieve breakthrough developments in treating various forms of cancer that could be of great value to our society," said Mr. Read.

ABOUT OXIS BIOTECH, INC. - Oxis Biotech develops innovative drugs focused on the treatment of cancer and other unmet medical needs. OXIS' lead drug candidate, DT2219ARL is a novel bispecific scFv recombinant fusion protein-drug conjugate composed of the variable regions of the heavy and light chains of anti-CD19 and anti-CD22 antibodies and a modified form of diphtheria toxin as its cytotoxic drug payload. DT2219ARL simultaneously targets cancer cells expressing the CD19 receptor or CD22 receptor or both receptors. When DT2219ARL binds to cancer cells, the cancer cells internalize DT2219ARL and are killed due to the action of drug's cytotoxic payload. DT2219ARL has demonstrated success in early human clinical trials in patients with relapsed/refractory B-cell lymphoma or leukemia. OXS-4235 is a small molecule therapeutic candidate targeting the treatment of multiple myeloma and associated osteolytic lesions. In in vitro and in vivo models of multiple myeloma and osteoporosis, OXS-4235 demonstrated the ability to kill multiple myeloma cells, and decrease osteolytic lesions in bone. OXIS' lead drug candidate, OXS-2175, is a small molecule therapeutic candidate targeting the treatment of triple-negative breast cancer (TNBC). In in vitro and in vivo models of TNBC, OXS-2175 demonstrated the ability to inhibit metastasis. For more information about Oxis Biotech, please visit http://www.oxis.com.

Forward-Looking Statements - Except for historical information contained herein, the statements in this release are forward-looking and made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are inherently unreliable and actual results may differ materially. Examples of forward-looking statements in this news release include statements regarding the payment of dividends, marketing and distribution plans, development activities and anticipated operating results. Factors which could cause actual results to differ materially from these forward-looking statements include such factors as the Company's ability to accomplish its business initiatives, significant fluctuations in marketing expenses and ability to achieve and expand significant levels of revenues, or recognize net income, from the sale of its products and services, as well as the introduction of competing products, or management's ability to attract and maintain qualified personnel necessary for the development and commercialization of its planned products, and other information that may be detailed from time to time in the Company's filings with the United States Securities and Exchange Commission. The Company undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

 

Oxis Biotech, Inc. Announces Appointment of James L. Nelson to Board
 

TAMPA, Fla., Sept. 15, 2015 -- Oxis Biotech, Inc. (OXIS), a wholly owned subsidiary of Oxis International, Inc. [OTC: OXIS] and [Euronext Paris: OXI.PA], announced today that James L. Nelson has joined its Business Advisory Board. Oxis is in the process of building a world class Advisory Board to assist management in strategy, development and execution. The Business Advisory Board members will become members of the Oxis Board of Directors upon a successful up-listing to the NASDAQ exchange.

James L. Nelson has served as a director and member of the audit committee of Icahn Enterprises L.P. (IEP) and its general partner, Icahn Enterprises G.P., Inc., since June 2001. Since June 2011, Mr. Nelson has served as a director and member of the compensation, governance and strategic alternatives committees of Voltari Corporation and, since January 2012, Chairman of its Board of Directors. Since April 2014, Mr. Nelson has served as a director and member of the audit committee, of Herbalife Ltd. (HLF), a nutrition company.

Mr. Nelson has previously served as a director and member of the audit committee of Tropicana Entertainment, The Viskase Companies, Inc., American Entertainment Properties, Atlantic Coast Entertainment Holdings, Inc., Cequel Communications, an owner and operator of a large cable television system, Take Two Interactive Software, Inc., a publisher, developer, and distributor of video games.

Mr. Nelson was Chairman and Chief Executive Officer of Eaglescliff Corporation, a specialty investment banking, consulting and wealth management company from 1986 through 2009. From 1995 through 1999, Mr. Nelson was Chief Executive Officer and Co-Chairman of Orbitex Management, Inc., a financial services company in the mutual fund sector.

"We are honored to have Jim as a member of our Business Advisory Board. Jim brings a wealth of experience and will help guide us while we complete the final requirements in our plans for up-listing to NASDAQ's main exchange," said Anthony Cataldo.

"I'm extremely pleased to be joining the Advisory Board of Oxis, and I look forward to being part of this exciting and socially rewarding industry," said Mr. Nelson.

ABOUT OXIS BIOTECH, INC. - Oxis Biotech develops innovative drugs focused on the treatment of cancer and other unmet medical needs. OXIS' lead drug candidate, DT2219ARL is a novel bispecific scFv recombinant fusion protein-drug conjugate composed of the variable regions of the heavy and light chains of anti-CD19 and anti-CD22 antibodies and a modified form of diphtheria toxin as its cytotoxic drug payload. DT2219ARL simultaneously targets cancer cells expressing the CD19 receptor or CD22 receptor or both receptors. When DT2219ARL binds to cancer cells, the cancer cells internalize DT2219ARL and are killed due to the action of drug's cytotoxic payload. DT2219ARL has demonstrated success in early human clinical trials in patients with relapsed/refractory B-cell lymphoma or leukemia. OXS-4235 is a small molecule therapeutic candidate targeting the treatment of multiple myeloma and associated osteolytic lesions. In in vitro and in vivo models of multiple myeloma and osteoporosis, OXS-4235 demonstrated the ability to kill multiple myeloma cells, and decrease osteolytic lesions in bone. OXIS' lead drug candidate, OXS-2175, is a small molecule therapeutic candidate targeting the treatment of triple-negative breast cancer (TNBC). In in vitro and in vivo models of TNBC, OXS-2175 demonstrated the ability to inhibit metastasis. For more information about Oxis Biotech, please visit http://www.oxis.com.

Forward-Looking Statements - Except for historical information contained herein, the statements in this release are forward-looking and made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are inherently unreliable and actual results may differ materially. Examples of forward-looking statements in this news release include statements regarding the payment of dividends, marketing and distribution plans, development activities and anticipated operating results. Factors which could cause actual results to differ materially from these forward-looking statements include such factors as the Company's ability to accomplish its business initiatives, significant fluctuations in marketing expenses and ability to achieve and expand significant levels of revenues, or recognize net income, from the sale of its products and services, as well as the introduction of competing products, or management's ability to attract and maintain qualified personnel necessary for the development and commercialization of its planned products, and other information that may be detailed from time to time in the Company's filings with the United States Securities and Exchange Commission. The Company undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

 

Oxis Biotech to present at the Rodman Renshaw Global Investment Conference
 

TAMPA, Fla., Sept. 9, 2015 -- Oxis Biotech, Inc. (OXIS), a wholly owned subsidiary of Oxis International, Inc. [OTC: OXIS] and [Euronext Paris: OXI.PA] announced today the company will be presenting at the 2015 Rodman & Renshaw Global Investment Conference in New York City.

Oxis Biotech Chairman and CEO Anthony J Cataldo is scheduled to present to investors on Thursday September 10, 2015 at 3:45pm. Mr. Cataldo will present details of Oxis' latest licensing agreement for DT2219ARL. DT2219ARL targets cancer cells expressing the CD19 receptor or CD22 receptor or both receptors. When DT2219ARL binds to cancer cells, the cancer cells internalize DT2219ARL and are killed due to the action of drug's cytotoxic payload. DT2219ARL has demonstrated success in early human clinical trials in patients with relapsed/refractory B-cell lymphoma or leukemia.

"We are very excited to update the investment community on the exciting developments at Oxis. DT2219ARL has the potential to be important and significant cancer drug," said Anthony J. Cataldo, Chairman and CEO of Oxis Biotech.

At the conference there will be opportunities for investors to meet one on one with Mr. Cataldo. Mr. Cataldo will be meeting with institutional investors and analysts throughout the week in New York. Investors interested in meeting with Mr. Cataldo should contact investor relations at the number provided below.

ABOUT OXIS BIOTECH, INC. - Oxis Biotech develops innovative drugs focused on the treatment of cancer and other unmet medical needs. OXIS' lead drug candidate, DT2219ARL is a novel bispecific scFv recombinant fusion protein-drug conjugate composed of the variable regions of the heavy and light chains of anti-CD19 and anti-CD22 antibodies and a modified form of diphtheria toxin as its cytotoxic drug payload. DT2219ARL simultaneously targets cancer cells expressing the CD19 receptor or CD22 receptor or both receptors. When DT2219ARL binds to cancer cells, the cancer cells internalize DT2219ARL and are killed due to the action of drug's cytotoxic payload. DT2219ARL has demonstrated success in early human clinical trials in patients with relapsed/refractory B-cell lymphoma or leukemia. OXS-4235 is a small molecule therapeutic candidate targeting the treatment of multiple myeloma and associated osteolytic lesions. In in vitro and in vivo models of multiple myeloma and osteoporosis, OXS-4235 demonstrated the ability to kill multiple myeloma cells, and decrease osteolytic lesions in bone. OXIS' lead drug candidate, OXS-2175, is a small molecule therapeutic candidate targeting the treatment of triple-negative breast cancer (TNBC). In in vitro and in vivo models of TNBC, OXS-2175 demonstrated the ability to inhibit metastasis. For more information about Oxis Biotech, please visit http://www.oxis.com.

Forward-Looking Statements - Except for historical information contained herein, the statements in this release are forward-looking and made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are inherently unreliable and actual results may differ materially. Examples of forward-looking statements in this news release include statements regarding the payment of dividends, marketing and distribution plans, development activities and anticipated operating results. Factors which could cause actual results to differ materially from these forward-looking statements include such factors as the Company's ability to accomplish its business initiatives, significant fluctuations in marketing expenses and ability to achieve and expand significant levels of revenues, or recognize net income, from the sale of its products and services, as well as the introduction of competing products, or management's ability to attract and maintain qualified personnel necessary for the development and commercialization of its planned products, and other information that may be detailed from time to time in the Company's filings with the United States Securities and Exchange Commission. The Company undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

Contact
Oxis International Inc.
Investor Relations
800-304-9888.

 

Oxis Biotech Licenses Exclusive Worldwide Rights To Novel Cancer Therapy
 

TAMPA, Fla., Sept. 8, 2015 -- Oxis Biotech, Inc. (OXIS), a wholly owned subsidiary of Oxis International, Inc. (OTC: OXIS) and (Euronext Paris: OXI.PA) announced today the execution of an exclusive worldwide license agreement to further develop and commercialize DT2219ARL, a novel therapy for the treatment of various human B cell cancers, leukemias and lymphomas.

DT2219ARL is a bispecific scFv recombinant fusion protein-drug conjugate composed of the variable regions of the heavy and light chains of anti-CD19 and anti-CD22 antibodies and a modified form of diphtheria toxin as its cytotoxic drug payload. CD19 is a membrane glycoprotein present on the surface of all stages of B lymphocyte development, and is also expressed on most B-cell mature lymphoma cells and leukemia cells.1 CD22 is a glycoprotein expressed on B-lineage lymphoid precursors, including precursor B acute lymphoblastic leukemia, and often is co-expressed with CD19 on mature B-cell malignancies such as lymphoma.2

DT2219ARL targets cancer cells expressing the CD19 receptor or CD22 receptor or both receptors. When DT2219ARL binds to cancer cells, the cancer cells internalize DT2219ARL and are killed due to the action of drug's cytotoxic payload. DT2219ARL has demonstrated success in early human clinical trials in patients with relapsed/refractory B-cell lymphoma or leukemia.

Twenty-five patients with advanced B-cell lymphoid malignancies expressing CD19 and/or CD22 were enrolled in a clinical study to evaluate DT2219ARL in a phase 1 FDA study. Patients were enrolled that had previous failed chemotherapy, immunotherapy, and/or hematopoietic (bone marrow or stem cell) transplantation. Patients received a single course of DT2219ARL according to study rules. Adverse events were successfully managed and included weight gain, low albumin, transaminitis, and fever were transient grade 1–2 and occurred in patients at the higher doses tested (>/=40µg/kg/day). Durable objective responses occurred in 2 patients at these higher doses. A complete response occurred in the only patient given a second cycle of therapy that had a 70% cancer reduction after the first cycle of therapy... The patient has been in remission for a year now. Correlative studies showed a surprisingly low incidence of neutralizing antibody (30%) production that could be related to the drug's ability to suppress antibody responses. For further information about the clinical trial, see Bachanova, V., et. al., Clin Cancer Res; 21(6) March 15, 2015.

"We are pleased to have the opportunity to further develop DT2219ARL", said Anthony J. Cataldo, Chairman and CEO of Oxis Biotech. There were several other major companies interested in acquiring this technology and we are honored to be the partner selected for this. This cancer therapy along with our existing platform, puts us in the forefront of next generation therapy along side companies like Amgen Biologics (AMGN), Seattle Genetics, Inc. (SGEN). When I started Lion Biotechnologies, Inc. (LBIO) in February of 2011, I knew that cell therapy was the next wave of cancer therapies to come. Kite Pharma (KITE) and Juno Therapeutics (JUNO) followed and demonstrated this. Now the future is targeted immunotherapy and with DT2219ARL, we are poised to lead this effort. "We believe DT2219ARL holds great promise as a treatment for a number of B-cell malignancies", Mr. Cataldo further added.

"We are very excited to continue this work with Oxis Biotech, said Dr. Daniel A Vallera, professor, University of Minnesota Masonic Cancer Center. "A stellar commercialization partner is critical at this juncture since our FDA trial is scheduled to resume with a superior dose scheduling involving multiple cycles of therapy. We expect even better responses with more aggressive treatment and need to move forward quickly."

B-cell malignancies represent a diverse number of cancers of the blood cells, lymph nodes and other parts of the lymphatic system, including non-Hodgkin's lymphomas, certain types of leukemia, and myelomas. Examples include chronic lymphocytic leukemia, follicular lymphoma, mantle cell lymphoma and diffuse large B-cell lymphoma.3

According to the Leukemia and Lymphoma Society, an estimated 1,185,053 people in the U.S. are either living with or are in remission from leukemia, lymphoma or myeloma, and approximately every 10 minutes someone in the U.S. dies from a blood-related cancer.4

ABOUT OXIS BIOTECH, INC. - Oxis Biotech develops innovative drugs focused on the treatment of cancer and other unmet medical needs. OXIS' lead drug candidate, DT2219ARL is a novel bispecific scFv recombinant fusion protein-drug conjugate composed of the variable regions of the heavy and light chains of anti-CD19 and anti-CD22 antibodies and a modified form of diphtheria toxin as its cytotoxic drug payload. DT2219ARL simultaneously targets cancer cells expressing the CD19 receptor or CD22 receptor or both receptors. When DT2219ARL binds to cancer cells, the cancer cells internalize DT2219ARL and are killed due to the action of drug's cytotoxic payload. DT2219ARL has demonstrated success in early human clinical trials in patients with relapsed/refractory B-cell lymphoma or leukemia. OXS-4235 is a small molecule therapeutic candidate targeting the treatment of multiple myeloma and associated osteolytic lesions. In in vitro and in vivo models of multiple myeloma and osteoporosis, OXS-4235 demonstrated the ability to kill multiple myeloma cells, and decrease osteolytic lesions in bone. OXIS' lead drug candidate, OXS-2175, is a small molecule therapeutic candidate targeting the treatment of triple-negative breast cancer (TNBC). In in vitro and in vivo models of TNBC, OXS-2175 demonstrated the ability to inhibit metastasis. For more information about Oxis Biotech, please visit http://www.oxis.com.

Forward-Looking Statements: Except for historical information contained herein, the statements in this release are forward-looking and made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are inherently unreliable and actual results may differ materially. Examples of forward-looking statements in this news release include statements regarding the payment of dividends, marketing and distribution plans, development activities and anticipated operating results. Factors which could cause actual results to differ materially from these forward-looking statements include such factors as the Company's ability to accomplish its business initiatives, significant fluctuations in marketing expenses and ability to achieve and expand significant levels of revenues, or recognize net income, from the sale of its products and services, as well as the introduction of competing products, or management's ability to attract and maintain qualified personnel necessary for the development and commercialization of its planned products, and other information that may be detailed from time to time in the Company's filings with the United States Securities and Exchange Commission. The Company undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

Contact Oxis International Inc.
Investor Relations
800-304-9888

1 Scheuermann RH, Racila E., Leuk. Lymphoma (1995) 18:385–97.
2 Cesano A, Gayko U., Semin. Oncol. (2003) 30:253–7.
3 National Comprehensive Cancer Network (2014).
4 Leukemia and Lymphoma Society FACTS 2014-2015.

 

Oxis Biotech Inc. Announces Appointment of Dr. James J Mulé to Scientific Advisory Board
 

TAMPA, Fla., Jan. 15, 2015 -- Oxis International, Inc. (OXIS) (OXI.PA) a biotechnology company focused on cannabinoid therapy development and commercialization, announced today, Dr. James J Mulé has joined the Scientific Advisory Board for its' wholly owned subsidiary, Oxis Biotech, Inc.

Dr. James J. Mulé, Ph.D. currently serves as an Executive Vice President and Associate Center Director for Translational Research, the Michael McGillicuddy Endowed Chair for Melanoma Research and Treatment, and the Co-Director of the Donald A. Adam Comprehensive Melanoma Center at the Moffitt Cancer Center. Previously, he was in Palo Alto, Calif., where he was involved in the birth of two startup companies while an adjunct faculty member in the Department of Surgery, Stanford University. He then moved to Ann Arbor, Mich., as the Director of the Tumor Immunology and Immunotherapy Clinical Research Program at the University of Michigan Comprehensive Cancer Center. Dr. Mulé is recognized for his translational research studies in cancer immunotherapy. His research group is involved in vaccine strategies and other approaches to stimulate the immune system to recognize and destroy tumors. The work in these areas has helped to develop new treatments for advanced cancer patients. Dr. Mulé serves on the Advisory Boards of seven NCI-designated Cancer Centers and was a member of the NCI's Board of Scientific and Clinical Counselors. He served as Chair of the Cellular, Tissue and Gene Therapy Advisory Committee of CBER, FDA, and is a Special Government Employee of the NCI and the FDA. Dr. Mulé is recognized for his research and clinical contributions to cancer immunotherapy, particularly in solid tumors.

Oxis Chairman and CEO Tony Cataldo stated, "We are honored to have Dr. Mulé on our Scientific Advisory Board. I was lucky enough to have Dr. Mulé on my SAB when I formed Genesis BioPharma (now Lion Biotechnologies, Inc.). His expertise and guidance in helping companies mature through the rigors of the FDA is invaluable to helping us advance our recently announced Multiple Myeloma Therapy."

"As a new member of the Oxis Biotech Scientific Advisory Board, I am delighted to once again have the unique opportunity to work with Mr. Cataldo on very promising, innovative strategies to address the world's significant cancer problem", said Dr. Mulé.

ABOUT OXIS BIOTECH, INC. - OXIS is a biotech company that develops and commercializes innovative drugs of therapeutic molecules including cannabinoids, which are focused on several cancer indications. Oxis address the clinical shortcomings of existing commercial products in related fields. OXIS has formed relationships with some of the world's leading cannabinoid researchers and institutions to advance its technologies.

Forward-Looking Statements: Except for historical information contained herein, the statements in this release are forward-looking and made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Forward-looking statements are inherently unreliable and actual results may differ materially. Examples of forward-looking statements in this news release include statements regarding the payment of dividends, marketing and distribution plans, development activities and anticipated operating results. Factors which could cause actual results to differ materially from these forward-looking statements include such factors as the Company's ability to accomplish its business initiatives, significant fluctuations in marketing expenses and ability to achieve and expand significant levels of revenues, or recognize net income, from the sale of its products and services, as well as the introduction of competing products, or management's ability to attract and maintain qualified personnel necessary for the development and commercialization of its planned products, and other information that may be detailed from time to time in the Company's filings with the United States Securities and Exchange Commission. The Company undertakes no obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

 

Oxis Biotech Executes Worldwide Exclusive Patent Licensing “P62 Chemical Agents and Multiple Myeloma Therapeutics” with Dr. Xiang-Qun (Sean) Xie, Professor of Pharmaceutical Sciences at University of Pittsburgh
 

Tampa , FL January 11, 2015 (PR NEWSWIRE) Oxis International, Inc. (OXIS)(OXI.PA) a biotechnology company focused on cannabinoid therapy development and commercialization, announced today, wholly owned subsidiary Oxis Biotech, Inc. executed definitive agreements licensing certain assets for the treatment of Multiple Myeloma and initiated a consulting agreement with University of Pittsburgh’s Professor, Dr. Xiang-Qun(Sean)Xie. The license agreement provides Oxis Biotech, Inc an exclusive worldwide license to develop and commercialize therapies for the treatment of Multiple Myeloma. Dr. Xie joins Oxis Biotech as a consultant and member of the Science Advisory Board to further develop the assets licensed to Oxis Biotech, Inc.

Sean Xie, MD, PhD, EMBA (one of the world’s foremost cannabinoid research scientists) is a tenured Professor at the Department of Pharmaceutical Sciences/Drug Discovery Institute at University of Pittsburgh and Associate Dean for Research Innovation at the School of Pharmacy. He is Principal Investigator of an integrated research laboratory of CompuGroup, BioGroup and ChemGroup, and Founding Director of Computational Chemical Genomics Screening Center. Dr. Xie is also Director/PI of NIH funded National Center of Excellence for Computational Drug Abuse Research. Dr. Xie holds joint faculty positions at the Departments of Computational System Biology and Structural Biology, and Pittsburgh Cancer Institute MT/DD Program. Xie is a charter member of the NIH BPNS Study Section Review Panel, an oversea expert reviewer for the Chinese Natural Science Foundation, ad hoc reviewer for the Netherlands Organizations for Scientific Research Council for Chemical Sciences, MCMB Foundation for MRC UK, and the Wellcome Trust Fund, Sir Henry Wellcome Fellowship, London, UK. He serves as an invited guest editor for AAPS Journal, Editorial Board of American Journal of Molecular Biology, and Associate Editor of BMC Pharmacology and Toxicology. He was an invited international Assessment Panelist for Fudan University College of Pharmacy, a member of the Board of Directors of the Chinese Association of Professionals in Science and Technology, and a Chair of the CAPST Biomedical and Pharmaceutical Society. Dr. Xie also holds adjunct professor title in top institutes and colleges of pharmacy in China, including CAMS Tianjin Institute of Hematology Stem Cell Medical Center; Fudan, Shanghai Jiaotong, and Zhejiang Universities. In 2013, he was named an honorary professor of Chinese Academy of Medical Sciences & Peking Union Medical College. Dr. Xie is a recipient of the 2014 American Association of Pharmaceutical Scientists (AAPS) Outstanding Research Achievement Award.

OXIS CEO Tony Cataldo stated, “Oxis is honored to have Dr. Xie and his patented technology as an integral part of our strategy to develop high valued patented assets for the treatment of Multiple Myeloma. I wanted to leverage Dr. Xie’s significant experience and technologies, much the same way I did when I acquired highly valued patents from the NCI (NIH) for stage 4 Melanoma from the National Cancer Institute to form Lion Biotechnologies, Inc. (LBIO)”.

Dr Xie said, “From the bench-to-clinic, there is often a barrier for an academic scientist to translate basic science research findings into valuable therapeutic interventions/patents which lead to drug therapy solutions because of a better understanding of disease process. This has been a dream of mine to pursue translational research and innovation drug discovery patents that have high value and can benefit our society and mankind. Now, we have an opportunity to establish this with our strategic partnership with Oxis Biotech, Inc.” Notably, “industry partnership” is also encouraged by University of Pittsburgh new Chancellor Patrick Gallagher who has had extensive high-level leadership in promoting U.S. innovation and industrial competitiveness by advancing measurement science, standards, and technology.

ABOUT OXIS BIOTECH, INC. - OXIS is a biotech company that develops and commercializes innovative drugs of therapeutic molecules including cannabinoids, which are focused on several cancer indications. Oxis address the clinical shortcomings of existing commercial products in related fields. OXIS has formed relationships with some of the worlds leading cannabinoid researchers and institutions to advance it's technologies.